Representation of somatosensory inputs within the cortical autonomic network

►Somatosensory inputs were represented in the insula and medial prefrontal cortex. ►Passive and volitional tasks differentially impacted cortical autonomic regions. ►Medial prefrontal cortex activity increased during Type I/II afferent stimulation. ►Medial prefrontal cortex activity decreased during isometric handgrip exercise. ►Medial prefrontal cortex activity was associated with heart rate variability.