Myelin water weighted diffusion tensor imaging

► Stimulated echo (STE) DTI acquisition preserves significantly more short T2 myelin water signal. ► Magnetization Transfer (MT) can provide additional differential sensitization to myelin water signal. ► Using MT-STE-DTI, sufficient sensitivity can be achieved to fit a myelin water weighted (MWW) diffusion tensor. ► MWW diffusion tensor exhibits larger FA mainly due to significantly smaller radial diffusivity.