Technical NoteDynamic correction of artifacts due to susceptibility effects and time-varying eddy currents in diffusion tensor imaging

In diffusion tensor imaging (DTI), spatial and temporal variations of the static magnetic field (B0) caused by susceptibility effects and time-varying eddy currents result in severe distortions, blurring, and misregistration artifacts, which in turn lead to errors in DTI metrics and in fiber tractography. Various correction methods have been proposed, but typically assume that the eddy current-induced magnetic field can be modeled as a constant or a single exponential decay within the DTI readout window. Here, we show that its temporal dependence is more complex because of the interaction of multiple eddy currents with different time constants, but that it remains very consistent over time. As such, we propose a novel dynamic B0 mapping and off-resonance correction method that measures the exact spatial, temporal, and diffusion-weighting direction dependence of the susceptibility- and eddy current-induced magnetic fields to effectively and efficiently correct for artifacts caused by both susceptibility effects and time-varying eddy currents, thereby resulting in a high spatial fidelity and accuracy.

389Highlights► Susceptibility effects and time-varying eddy currents cause severe artifacts in DTI. ► Eddy current-induced magnetic fields vary substantially within the readout window. ► They cannot be modeled as a constant or a monoexponential decay, as usually assumed. ► A novel dynamic off-resonance correction method is proposed to address these issues. ► This method can effectively and efficiently correct for both types of artifacts.