کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6037386 | 1188787 | 2010 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Modeling hemodynamic responses in auditory cortex at 1.5Â T using variable duration imaging acoustic noise
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Modeling hemodynamic responses in auditory cortex at 1.5Â T using variable duration imaging acoustic noise Modeling hemodynamic responses in auditory cortex at 1.5Â T using variable duration imaging acoustic noise](/preview/png/6037386.png)
چکیده انگلیسی
A confound for functional magnetic resonance imaging (fMRI), especially for auditory studies, is the presence of imaging acoustic noise generated mainly as a byproduct of rapid gradient switching during volume acquisition and, to a lesser extent, the radiofrequency transmit. This work utilized a novel pulse sequence to present actual imaging acoustic noise for characterization of the induced hemodynamic responses and assessment of linearity in the primary auditory cortex with respect to noise duration. Results show that responses to brief duration (46Â ms) imaging acoustic noise is highly nonlinear while responses to longer duration (>1Â s) imaging acoustic noise becomes approximately linear, with the right primary auditory cortex exhibiting a higher degree of nonlinearity than the left for the investigated noise durations. This study also assessed the spatial extent of activation induced by imaging acoustic noise, showing that the use of modeled responses (specific to imaging acoustic noise) as the reference waveform revealed additional activations in the auditory cortex not observed with a canonical gamma variate reference waveform, suggesting an improvement in detection sensitivity for imaging acoustic noise-induced activity. Longer duration (1.5Â s) imaging acoustic noise was observed to induce activity that expanded outwards from Heschl's gyrus to cover the superior temporal gyrus as well as parts of the middle temporal gyrus and insula, potentially affecting higher level acoustic processing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 49, Issue 4, 15 February 2010, Pages 3027-3038
Journal: NeuroImage - Volume 49, Issue 4, 15 February 2010, Pages 3027-3038
نویسندگان
Shuowen Hu, Olumide Olulade, Javier Gonzalez Castillo, Joseph Santos, Sungeun Kim, Gregory G. Jr., Wen-Ming Luh, Thomas M. Talavage,