کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6039770 1188825 2008 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Normalization in PET group comparison studies-The importance of a valid reference region
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Normalization in PET group comparison studies-The importance of a valid reference region
چکیده انگلیسی
Ratio normalization to the global mean readily elevates CBF in unchanged regions when a systematic between-group difference exists in gCBF, also when this difference is below the detection threshold. We suggest that the routine normalization to the global mean in earlier studies resulted in spurious interpretations of perturbed CBF. Normalization to central WM yields less biased results in aging and HE and could potentially serve as a normalization reference region in other disorders as well.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 40, Issue 2, 1 April 2008, Pages 529-540
نویسندگان
, , , , , , , , ,