Microwave-assisted preparation of N-doped carbon dots as a biosensor for electrochemical dopamine detection

A new N-doped carbon dots (NCDs) could be prepared by using the microwave-assisted technique within 10 min without the need for any solvent or catalyst. The NCDs exhibited a highly sensitive electrochemical response toward dopamine (DA) in Phosphate Buffered Saline (PBS) (pH = 6.5). The detection limit of DA was calculated by differential pulse voltammetry (DPV) as low as 1.2 × 10−9 mol/L with a linear dynamic range of 5.0 × 10−8 to 8.0 × 10−6 mol/L. These results suggested that this new NCDs could be effectively used for the direct and rapid detection of trace levels of DA in human serum and urine samples.

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