Investigation of the reversibility of the unimer-to-aggregate transition in block copolymers by surface tension-measurements

► Biohybrids were obtained by coupling short oligonucleotides to synthetic polymers. ► These new block copolymers form “DNA-micelles”. ► Self-assembly of these bioconjugates can be probed by surface tension measurements. ► It is demonstrated that their assemblies are reversible.