کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
608620 880604 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Substrate effects on interactions of lipid bilayer assemblies with bound nanoparticles
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Substrate effects on interactions of lipid bilayer assemblies with bound nanoparticles
چکیده انگلیسی

Understanding the interactions of nanoparticles with lipid membranes is crucial in establishing the mechanisms that govern assembly of membrane-based nanocomposites, nanotoxicology, and biomimetic inspired self-assembly. In this study, we explore binding of charged nanoparticles to lipid bilayers, both as liposomes and substrate supported assemblies. We find that the presence of a solid-support, regardless of curvature, eliminates the ability of zwitterionic fluid phase lipids to bind charged nanoparticles.

Schematic description of the influence of a substrate on the binding of charged nanoparticles to a zwitterionic lipid bilayer.Figure optionsDownload high-quality image (78 K)Download as PowerPoint slideHighlights
► Supported lipid bilayers versus bilayer vesicles respond differently to nanoparticles.
► Solid supports limit lipid reconfiguration that allows for nanoparticle binding.
► The effect is limited to zwitterionic lipids.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Colloid and Interface Science - Volume 358, Issue 2, 15 June 2011, Pages 635–638
نویسندگان
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