Occasional articlePerspectives on interventional diabetology: Duodenal exclusion is promising for human type 2 diabetes mellitus remission

- Type 2 diabetes mellitus (T2DM) is common in obese as well as nonobese patients.
- Obese patients with T2DM undergoing bariatric surgery for weight loss show improved glycemic control.
- Different bariatric surgeries for obese patients with T2DM have different outcomes in weight loss and remission rates of T2DM.
- The effects of bariatric surgery in nonobese patients with T2DM on weight loss and glucose homeostasis continue to be investigated.
- Other antiobesity interventions, such as endoscopic duodenal-jejunal bypass liner with a barrier effect from duodenal exclusion, prevent detrimental metabolic effects.