کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6089752 1208551 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Brief reportEffect of buttermilk consumption on blood pressure in moderately hypercholesterolemic men and women
ترجمه فارسی عنوان
گزارش مختصر تأثیر مصرف پستان در فشار خون در مردان و زنان دارای هیپرکلسترولمی متوسط
کلمات کلیدی
پپتید های زیست فعال بادامک، فشار خون، سیستم آلدسترون سیستم آنژیوتانسین رینین؟ غشای چربی چربی شیر،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

ObjectivesMilk fat globule membrane (MFGM) found in buttermilk is rich in unique bioactive proteins. Several studies suggest that MFGM proteins possess biological activities such as cholesterol-lowering, antiviral, antibacterial, and anticancer properties, but data in humans are lacking. Furthermore, to our knowledge, no study has yet investigated the antihypertensive potential of MFGM proteins from buttermilk. The aim of this study was to investigate the effects of buttermilk consumption on blood pressure and on markers of the renin-angiotensin-aldosterone (RAS) system in humans.MethodsMen and women (N = 34) with plasma low-density lipoprotein cholesterol < 5 mmol/L and normal blood pressure (< 140 mm Hg) were recruited in this randomized, double-blind, placebo-controlled, crossover study. Their diets were supplemented with 45 g/d of buttermilk and with 45 g/d of a macro-/micronutrient-matched placebo in random order (4 wk for each diet).ResultsButtermilk consumption significantly reduced systolic blood pressure (−2.6 mm Hg; P = 0.009), mean arterial blood pressure (−1.7 mm Hg; P = 0.015), and plasma levels of the angiotensin I-converting enzyme (−10.9%; P = 0.003) compared with the placebo, but had no effect on plasma concentrations of angiotensin II and aldosterone.ConclusionShort-term buttermilk consumption reduces blood pressure in normotensive individuals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 30, Issue 1, January 2014, Pages 116-119
نویسندگان
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