کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6110636 | 1211534 | 2016 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency
ترجمه فارسی عنوان
خلاصه و پیشنهادات از دستورالعمل استرالیا برای مدیریت نارسایی مزمن لوزالمعده
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
چکیده انگلیسی
Recent studies confirm that patients with chronic pancreatitis receive similar benefit from pancreatic exocrine replacement therapy (PERT) to that established in children with cystic fibrosis. Severe acute pancreatitis is frequently followed by PEI and PERT should be considered for these patients because of their nutritional requirements. Evidence is also becoming stronger for the benefits of PERT in patients with unresectable pancreatic cancer. However there is as yet no clear guide to help identify those patients in the 'unlikely' PEI group who would benefit from PERT. For example, patients with coeliac disease, diabetes mellitus, irritable bowel syndrome and weight loss in the elderly may occasionally be given a trial of PERT, but determining its effectiveness will be difficult. The starting dose of PERT should be from 25,000-40,000 IU lipase taken with food. This may need to be titrated up and there may be a need for proton pump inhibitors in some patients to improve efficacy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pancreatology - Volume 16, Issue 2, MarchâApril 2016, Pages 164-180
Journal: Pancreatology - Volume 16, Issue 2, MarchâApril 2016, Pages 164-180
نویسندگان
Working Party of the Australasian Pancreatic Club: Working Party of the Australasian Pancreatic Club:, Ross C. Smith, Sarah F. Smith, Jeremy Wilson, Callum Pearce, Nick Wray, Ruth Vo, John Chen, Chee Y. Ooi, Mark Oliver, Tamarah Katz, Richard Turner,