Hydroxyapatite micro- and nanoparticles: Nucleation and growth mechanisms in the presence of citrate species

Hydroxyapatite (HAP) particles with different morphologies were precipitated from homogeneous calcium/citrate/phosphate solutions at physiological temperature. Small variations of the starting solution pH in the range 7.4

Hydroxyapatite particles were precipitated from calcium/citrate/phosphate solutions at 37 °C. Solution pH variations induced morphology changes from micrometric bundle- to nanometric needle-like shapes. The role of citrate species during particle nucleation and growth is here discussed.Figure optionsDownload as PowerPoint slide