کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6115965 1215939 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Distribution of AdeABC efflux system genes in genotypically diverse strains of clinical Acinetobacter baumannii
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Distribution of AdeABC efflux system genes in genotypically diverse strains of clinical Acinetobacter baumannii
چکیده انگلیسی
Acinetobacter baumannii has emerged as a highly problematic hospital-associated pathogen. Different mechanisms contribute to the formation of multidrug resistance in A. baumannii, including the AdeABC efflux system. Distribution of the structural and regulatory genes encoding the AdeABC efflux system among genetically diverse clinical A. baumannii strains was achieved by using PCR and pulsed-field gel electrophoresis techniques. The distribution of adeABRS genes is extremely high among our A. baumannii strains, except the adeC gene. We have observed a large proportion of strains presenting multidrug-resistance phenotype for several years. The efflux pump could be an important mechanism in these strains in resistance to antibiotics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 77, Issue 2, October 2013, Pages 106-109
نویسندگان
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