Is loss in femorotibial cartilage thickness related to severity of contra-lateral radiographic knee osteoarthritis? - Longitudinal data from the Osteoarthritis Initiative

KLG2 knees with JSN and moderate contra-lateral RKOA, display relatively high rates of subregional femorotibial cartilage loss, despite being at a relatively mild stage of RKOA. They may therefore provide a unique opportunity for recruitment in clinical trials that explore the efficacy of anti-catabolic DMOADs on structural progression.