کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6125657 1220235 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation
چکیده انگلیسی
The convenient isolation technique enables the easy generation of sufficient MSC to permit the molecular analysis of their differentiation. We were thus able to show that the proinflammatory cytokines, IL-1β and TNFα, can compromise bone development from this primary MSC population, although with some significant differences. The potential involvement of specific inflammatory mediators needs to be taken into account if optimal bone repair and presumably that of other tissues are to be achieved with MSC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Osteoarthritis and Cartilage - Volume 17, Issue 6, June 2009, Pages 735-742
نویسندگان
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