کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6145984 1594927 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel single nucleotide polymorphisms in the superoxide dismutase 1 and 2 genes among children with myelomeningocele
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Novel single nucleotide polymorphisms in the superoxide dismutase 1 and 2 genes among children with myelomeningocele
چکیده انگلیسی
We identified 1 novel variant and made the second report of an additional variant in the SOD genes studied. The variant located in the 3′-UTR of SOD1 is predicted to alter microribonucleic acid (miRNA) binding. The variant located in the 3′-UTR of SOD2 is predicted to alter 2 miRNA binding sites and potentially affects messenger ribonucleic acid production. We also identified 2 known single-nucleotide polymorphisms that occur in significantly different frequency compared with the unaffected population controls.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Obstetrics and Gynecology - Volume 209, Issue 4, October 2013, Pages 388.e1-388.e7
نویسندگان
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