کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6157033 | 1598242 | 2016 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diagnosis and Management of Iron Deficiency in CKD: A Summary of the NICE Guideline Recommendations and Their Rationale
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
diagnostic tests - آزمایش های تشخیصیIntravenous iron - آهن داخل وریدیerythropoietin - اریتروپویتینinflammation - التهاب( توروم) Chronic kidney disease (CKD) - بیماری مزمن کلیه (CKD)Hypersensitivity - حساسیت بیش از حدIron therapy - درمان آهنClinical practice guideline - دستورالعمل تمرین بالینیHemodialysis - همودیالیزIron overload - هموکروماتوزAnemia - کم خونیIron deficiency - کمبود آهن
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Diagnosis and Management of Iron Deficiency in CKD: A Summary of the NICE Guideline Recommendations and Their Rationale Diagnosis and Management of Iron Deficiency in CKD: A Summary of the NICE Guideline Recommendations and Their Rationale](/preview/png/6157033.png)
چکیده انگلیسی
The UK-based National Institute for Health and Care Excellence (NICE) has updated its guidance on iron deficiency and anemia management in chronic kidney disease. This report outlines the recommendations regarding iron deficiency and their rationale. Serum ferritin alone or transferrin saturation alone are no longer recommended as diagnostic tests to assess iron deficiency. Red blood cell markers (percentage hypochromic red blood cells, reticulocyte hemoglobin content, or reticulocyte hemoglobin equivalent) are better than ferritin level alone at predicting responsiveness to intravenous iron. When red blood cell markers are not available, a combination of transferrin saturation < 20% and ferritin level < 100 ng/mL is an alternative. In comparisons of the cost-effectiveness of different iron status testing and treatment strategies, using percentage hypochromic red blood cells > 6% was the most cost-effective strategy for both hemodialysis and nonhemodialysis patients. A trial of oral iron replacement is recommended in people not receiving an erythropoiesis-stimulating agent (ESA) and not on hemodialysis therapy. For children receiving ESAs, but not treated by hemodialysis, oral iron should be considered. In adults and children receiving ESAs and/or on hemodialysis therapy, intravenous iron should be offered. When giving intravenous iron, high-dose low-frequency administration is recommended. For all children and for adults receiving in-center hemodialysis, low-dose high-frequency administration may be more appropriate.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 67, Issue 4, April 2016, Pages 548-558
Journal: American Journal of Kidney Diseases - Volume 67, Issue 4, April 2016, Pages 548-558
نویسندگان
Laura E.K. MRCP, Wayne FRCPath, Jessica MSc, Smita MBBS, MPH, Ben A.J. BSc, David MSc, Roy RN (Child), MSc, Suzanne MBBS, FRCPCH, Ashraf I. MD, FRCP, Damian G. MD, Jan K. Cooper, Belinda BSc, MPH, Mark A.J. FRCPE, Chris MPharm, Mark E. FRCP,