کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6158276 1598318 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapidly Progressive Severe Vascular Calcification Sparing the Kidney Allograft Following Warfarin Initiation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Rapidly Progressive Severe Vascular Calcification Sparing the Kidney Allograft Following Warfarin Initiation
چکیده انگلیسی
We describe a case of rapid onset of vascular calcification coincident with the initiation of warfarin therapy in a kidney transplant recipient. Calcification developed within the media of the blood vessel wall, with relative intimal sparing. Medium and small arteries were affected; however, the aorta was mostly free of calcifications, suggesting a differential response to warfarin between the intima and media and between different vascular beds. In addition, unlike the highly calcified native kidney's vessels, the kidney allograft was not calcified, suggesting local genetically determined mechanisms in preventing vascular calcification. Distal subcutaneous necrosis ultimately led to the patient's death.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 56, Issue 6, December 2010, Pages 1158-1162
نویسندگان
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