کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6169965 | 1251186 | 2015 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Tumour infiltrating lymphocytes (TILs) in breast cancer during pregnancy
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Tumour infiltrating lymphocytes (TILs) in breast cancer during pregnancy Tumour infiltrating lymphocytes (TILs) in breast cancer during pregnancy](/preview/png/6169965.png)
چکیده انگلیسی
BackgroundTumour infiltrating lymphocytes (TILs) is one of the most exciting breast cancer biomarkers, yet no data is available on its prevalence in tumours diagnosed during pregnancy.MethodsWe evaluated the prevalence of TILs (stromal and intratumoural) in pregnant and non-pregnant young breast cancer patients.Results11/116 (9.6%) of the non-pregnant and 2/86 (2.3%) pregnant patients had TILs â¥Â 50% (p < 0.001) with highest prevalence observed in triple negative tumours (p = 0.01).ConclusionsThis is the first report on TILs in tumours diagnosed during pregnancy. The low prevalence could reflect the state of low host immunity associated with pregnancy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Breast - Volume 24, Issue 3, June 2015, Pages 290-293
Journal: The Breast - Volume 24, Issue 3, June 2015, Pages 290-293
نویسندگان
Hatem A. Jr., Andrea Vingiani, Fedro Peccatori, Giuseppe Viale, Sherene Loi, Giancarlo Pruneri,