کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6171171 | 1251424 | 2015 | 7 صفحه PDF | دانلود رایگان |
BackgroundBreast milk volume has never been evaluated when the etonogestrel (ENG) implant was inserted immediately postpartum. Thus, this study evaluated if the immediate postpartum insertion of the ENG implant alters breast milk volume.Study designTwenty-four postpartum women and their newborns (NBs) were randomized into two groups: Implant group (ENG implant inserted within 48Â h after delivery) and Control group (absence of contraceptive method). The primary outcome was the amount of breast milk intake by the NBs in the first 6Â weeks after delivery. Five and ten grams of deuterium (D2O) were orally administered to the postpartum women on the day of randomization (day 0) and on the 29th study day, respectively. Saliva samples were collected from the mother-NB pairs prior to each D2O dose administration and after D2O ingestion (periodic collection). The amount of breast milk ingested by the NBs was estimated by the amount of deuterium (D2O) ingested by the NBs through breastfeeding, using mass spectrometry in the saliva samples.ResultsTwenty-four postpartum women and their NB were randomized (12 per group). The median of breast milk intake by NBs following the two D2O doses were similar between groups {first D2O dose [Implant: 340Â mL/day (240-420Â mL/day) vs. Control: 330Â mL/day (300-530Â mL/day), p=.54]; second D2O dose [Implant: 845Â mL/day (770-980Â mL/day) vs. Control: 785Â mL/day (680-980Â mL/day), p=.63]}. The exclusive breastfeeding rate and NB weight were similar between groups in the first 6Â weeks postpartum.ConclusionENG implant insertion immediately postpartum does not alter the volume of breast milk intake by NBs.ImplicationsConsidering the benefits of immediate postpartum initiation of ENG implant on reducing unintended pregnancy and pregnancy recurrence, especially in vulnerable populations, our study adds safety data on breastfeeding effect of this practice.
Journal: Contraception - Volume 92, Issue 6, December 2015, Pages 536-542