کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6188908 1256699 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Coasting, embryo development and outcomes of blastocyst transfer: a case-control study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Coasting, embryo development and outcomes of blastocyst transfer: a case-control study
چکیده انگلیسی

This study compared the effect on blastocyst development and clinical outcome of coasting in women at increased risk of moderate-severe ovarian hyperstimulation syndrome (OHSS; n = 389) with a control group matched for age and basal FSH that did not undergo coasting (n = 386) in IVF/intracytoplasmic sperm injection (ICSI) cycles. The main outcome measures were rate of blastocyst development and live birth. More cycles progressed to the blastocyst stage in the coasted group (n = 169) compared with the control group (n = 83; 43.4% versus 21.5%; P < 0.001). The biochemical pregnancy, clinical pregnancy and live birth rates were similar (46.5% versus 42.0%; 40.6% versus 37.8%; 31.6% versus 30.1%). The duration of coasting up to 4 days did not affect progression to blastocyst stage. The multivariate model showed that coasting (OR 1.73, P = 0.004) and the number of oocytes retrieved (OR 1.17, P = 0.001) were positively correlated with blastocyst formation. Coasting, a measure to reduce the risk of OHSS, does not impair blastocyst development or clinical outcome. Coasting should remain an effective measure to prevent OHSS.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive BioMedicine Online - Volume 29, Issue 2, August 2014, Pages 231-238
نویسندگان
, , , , , , ,