کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6203947 1263520 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optical anisotropies in corneal stroma collagen fibers from diabetic spontaneous mice
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Optical anisotropies in corneal stroma collagen fibers from diabetic spontaneous mice
چکیده انگلیسی

In this work, optical retardation (OR) was investigated in corneal stroma collagen fibers from nonobese diabetic (NOD) and healthy (BALB/c) mice. Linear dichroism (LD) was investigated in corneas stained with Ponceau SS and Toluidine Blue, using microspectrophotometer. NOD corneas showed higher OR values than the control. Ponceau SS-complexed collagen fibers showed positive LD that was higher for NOD corneas. After staining with Toluidine Blue, NOD and BALB/c corneas showed negative LD. The results of this study demonstrate that diabetes was capable of altering the corneal optical anisotropies, possibly altering the number of intermolecular crosslinks in collagen fibers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vision Research - Volume 47, Issue 26, December 2007, Pages 3229-3237
نویسندگان
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