کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6209984 | 1604018 | 2013 | 4 صفحه PDF | دانلود رایگان |
Teratogenic effects of polymethylmethacrylate cement at levels used during routine orthopaedic procedures have never been reported, however the hypothetical risk remains a major concern among female surgeons. Our aim was to determine if methyl methacrylate is detectible in the serum during routine cement exposure. Methods: Twenty healthy volunteers were exposed during the mixing of polymethylmethacrylate cement in a simulated operating room environment. Forty serum samples were obtained during the expected peak inhalational exposure and levels of methyl methacrylate were assessed utilizing headspace gas chromatography mass spectrometry. Results: Methyl methacrylate was not detected in any of the forty experimental specimens. Conclusions: With a detection level of 0.5 ppm, methyl methacrylate is undetectable in the serum during routine mixing of polymethylmethacrylate cement.
Journal: The Journal of Arthroplasty - Volume 28, Issue 3, March 2013, Pages 406-409