کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6211310 1267213 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Histological features of the ACL remnant in partial tears
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
Histological features of the ACL remnant in partial tears
چکیده انگلیسی


- Histology of the ACL remnants has not been studied.
- There is a normal femoral insertion of the remnant in 22.7% of cases.
- There are still blood vessels and nerve endings in the ACL remnant in partial tears.

BackgroundThe aim of this study was to investigate the histological features of the remaining fibers bridging the femur and tibia in partial ACL tears.MethodsTwenty-six ACL remnants were harvested from patients who had arthroscopic criteria concordant with a partial tear. Histological analysis includes cellularity, blood vessel density evaluation and characterization of the femoral bony insertion morphology. Immunohistochemical studies were carried out to determine cells positive for α-smooth actin and for mechanoreceptor detection.ResultsIn these samples, a normal femoral insertion of the remnant was present in 22.7% of the cases. In 54% of the samples, substantial areas of hypercellularity were observed. Myofibroblasts were the predominant cell type and numerous cells positive for α-smooth actin were detected at immunostaining. Blood vessel density was increased in hypercellularity areas and in the synovial sheet. Free nerve endings and few Golgi or Ruffini corpuscles were detected in 41% of the specimens. The cellularity was correlated to the time between injury to surgery (p = 0.001).ConclusionCompetent histological structures including a well-vascularized synovial sheet, numerous fibroblasts and myofibroblasts and mechanoreceptors were found in ACL remnants. These histological findings bring additional knowledge towards the preservation of the ACL remnant in partial tears when ACL reconstruction or augmentation is considered.Clinical relevanceDescriptive laboratory study.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Knee - Volume 21, Issue 6, December 2014, Pages 1009-1013
نویسندگان
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