کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6218082 1273793 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The association of adrenocortical carcinoma and thyroid cancer in a child with Peutz-Jeghers syndrome
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
The association of adrenocortical carcinoma and thyroid cancer in a child with Peutz-Jeghers syndrome
چکیده انگلیسی

Peutz-Jeghers syndrome (PJS) is a rare, dominantly inherited disorder characterized by gastrointestinal hamartomatous polyps, mucocutaneous hyperpigmentation, and an increased risk of cancer. We present a 16-month-old child diagnosed with PJS, who had distinguishing features compared with the previously reported cases with respect to her clinical presentation, associated malignancies, and genetic analysis. To our knowledge, this is the first report of adrenocortical carcinoma in association with PJS, as well as the first instance of associated thyroid cancer in a child with PJS. We briefly review the relevant literature and highlight the recent progress achieved in the investigation of the syndrome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Surgery - Volume 46, Issue 3, March 2011, Pages 570-573
نویسندگان
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