کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6218731 | 1607423 | 2016 | 10 صفحه PDF | دانلود رایگان |
ObjectiveTo examine the efficacy of a phonics-training program in children with neurofibromatosis type 1 (NF1) and reading difficulties.Study designThirty children (7-12 years of age) with NF1 completed a double-baseline, 24-week intervention trial. Literacy outcome measures were assessed at 4 time points: (1) at baseline; (2) after an 8-week no-treatment period; (3) immediately post-treatment; and (4) at follow-up 8 weeks post-treatment. Repeated-measures ANOVA were conducted to examine change over time for all outcome measures, and significant main effects were explored with planned comparisons. Predictors of treatment effects were examined by linear regressions.ResultsNinety percent of participants completed the intervention. Intervention-specific improvements were observed across a range of literacy outcomes, including reading accuracy (nonword reading, Cohen dâ=â1.10; regular-word reading, Cohen dâ=â0.32), letter-sound knowledge (Cohen dâ=â0.80), blending (Cohen dâ=â0.88), repetition of nonsense words (Cohen dâ=â0.94), phonemic decoding fluency (Cohen dâ=â0.55), and reading comprehension (Cohen dâ=â0.31). Improvements were maintained 8 weeks post-treatment. Age (Pâ=â.03) and working memory (Pâ=â.02) significantly influenced efficacy, with greatest improvements observed in older children with stronger verbal working memory capacity.ConclusionsHome-based, computerized reading intervention was effective in improving the reading and reading-related abilities of children with NF1 and reading difficulty.Trial registrationAustralian and New Zealand Clinical Trials Registry: ACTRN12611000779976
Journal: The Journal of Pediatrics - Volume 177, October 2016, Pages 219-226.e2