کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6229607 1608121 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changing depressive symptoms following percutaneous coronary intervention, clustering and effect on adherence - The THORESCI study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
پیش نمایش صفحه اول مقاله
Changing depressive symptoms following percutaneous coronary intervention, clustering and effect on adherence - The THORESCI study
چکیده انگلیسی


- Depressive symptoms cluster in their change over time.
- Cognitive-affective, somatic-affective, and severe cognitive symptoms changed separately.
- The predictive value of depression depends on the preceding depression trajectory.

BackgroundDepressive symptom dimensions may have a differential effect on cardiac prognosis. It is yet unknown whether and how depressive symptoms change together over time and how this may affect disease progression. We examined the clustering of changing depressive symptoms over the first 6 months after percutaneous coronary intervention (PCI), and examined the influence of the change profile on the predictive value of depression for treatment adherence at 6 months post-PCI.MethodsPCI patients (N=219, age: 62±15, 20% women) reported on depressive symptoms (PHQ-9, BDI; 30 symptoms) and adherence (MOS-GAS) at 1 and 6 months post-PCI. Principal component analysis (PCA) was performed on the individual symptom change scores. Multivariable linear regression examined the role of change profiles in predicting general treatment adherence, while adjusting for demographic and clinical characteristics.ResultsFour change-factors emerged from PCA. One somatic-affective change-factor (10 symptoms), two cognitive-affective change-factors (6 general cognitive-affective and 7 severe cognitive symptoms) and one mixed factor were identified. We extracted 5 symptom change profiles. Linear regression showed the moderating role of the change profiles. In patients reporting a net increase in depressive symptoms, higher cognitive affective symptoms (β=−.46, p=.001) and higher somatic-affective symptoms (β=−.29; p=.044) were associated with worse general adherence.DiscussionFour distinct depressive symptom change-factors were identified that moderated the association of somatic-affective and cognitive-affective depressive symptom levels with general treatment adherence. This is of clinical importance as not only current symptoms, but also symptom change over the preceding months may be important to consider in screening and risk prediction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 204, 1 November 2016, Pages 146-153
نویسندگان
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