کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6232472 1608159 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Persistence in the long term of the effects of a collaborative care programme for depression in primary care
ترجمه فارسی عنوان
پایداری در بلند مدت از اثرات یک برنامه مراقبت مشترک برای افسردگی در مراقبت های اولیه
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی

BackgroundA collaborative care programme for depression in primary care has proven clinical effectiveness over a 12-months period. Because depression tends to relapse and to chronic course, our aim was to determine whether the effectiveness observed in the first year persists during 3 years of monitoring.MethodsRandomised controlled trial with twenty primary care centres were allocated to intervention group or usual care group. The intervention consisted of a collaborative care programme with clinical, educational and organisational procedures. Outcomes were monitored by a blinded interviewer at baseline, 12 and 36 months. Clinical outcomes were response to treatment and remission rates, depression severity and health-related quality of life. Trial registration: ISRCTN16384353.ResultsA total of 338 adult patients with major depression (DSM-IV) were assessed at baseline. At 36 months, 137 patients in the intervention group and 97 in the control group were assessed (attrition 31%). The severity of depression (mean Patient Health Questionnaire-9 score) was 0.95 points lower in the intervention group [6.31 versus 7.25; p=0.324]. The treatment response rate was 5.6% higher in the intervention group than in the control group [66.4% versus 60.8%; p=0.379] and the remission rate was 9.2% higher [57.7% versus 48.5%; p=0.164]. No difference reached statistical significance.LimitationsThe number of patients lost (31%) before follow-up may have introduced a bias.ConclusionsClinical benefits shown in the first year were not maintained beyond: at 36 months the differences between the control group and the intervention group reduced in all the analysed variables.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 166, September 2014, Pages 36-40
نویسندگان
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