کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6247978 | 1284524 | 2012 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Organ donation and allocationOrgan allocationKidney Transplantation Using Donors Over 70 Years Old: Are the Criteria for Organ Allocation Too Expanded? Organ donation and allocationOrgan allocationKidney Transplantation Using Donors Over 70 Years Old: Are the Criteria for Organ Allocation Too Expanded?](/preview/png/6247978.png)
BackgroundThe scarcity of organs available for transplantation has led to the use of kidneys from old deceased donors including those â¥70 years of age. The results of kidney transplants performed using such “limit” organs warrent further study.MethodsWe retrospectively evaluated all cadaveric heart-beating renal transplants performed from September 1996 to June 2010 using expanded-criteria donors: Group 1 included 302 transplants performed with kidneys from expanded-criteria donors aged 50-69 years; group 2 included 60 recipients of kidneys from donors aged â¥70 years. All patients were prescribed an immunossupressive regimen based on mycophenolate mofetil or mycophenolic acid, a calcineurin inhibitor, and corticosteroids, with or without monoclonal/polyclonal antibodies.ResultsThe baseline recipient characteristics were similar except for age, which was higher in group 2; history of previous transplantation was absent in group 2, and there was more use of induction with monoclonal or polyclonal antibodies in group 2 (65% vs 49%; P = .02). There was no significant difference in the rate of nonfunctioning grafts, delayed graft function, or acute rejection episodes in the first 6 months. There was no significant difference between groups regarding graft or patient survival.ConclusionsThe use of kidneys from donors aged â¥70 older than or years yielded generally satisfactory results.
Journal: Transplantation Proceedings - Volume 44, Issue 8, October 2012, Pages 2289-2292