Endotoxin Tolerance Attenuates Liver Ischemia/Reperfusion Injury by Down-Regulation of Interleukin-1 Receptor-Associated Kinase 4 in Kupffer Cells

Endotoxin preconditioning attenuated the liver I/R injury caused by transplantation. The expression of IRAK-4 in KCs may play an important role in the formation of ET.