کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6249889 1284572 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The 9th Korea-Japan transplantation forumProcurement and preservationDoes Procurement Technique Affect Posttransplant Graft Function in Deceased Donor Liver Transplantation?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
The 9th Korea-Japan transplantation forumProcurement and preservationDoes Procurement Technique Affect Posttransplant Graft Function in Deceased Donor Liver Transplantation?
چکیده انگلیسی

IntroductionVarious techniques have been described deceased donor liver transplantation (DDLT) procurement. One is a technique whereby almost total dissection is done in the porta hepatis and perihepatic detachment is carried out before cross-clamping the donor aorta. In another approach, after the donor aorta is cross-clamped, rapid and minimal en bloc dissection is performed with minimal manipulation. We evaluated early posttransplant graft function among liver procurement techniques.MethodBetween January 2008 and August 2012, we performed 45 consecutive adult DDLTs. One patient was excluded from this analysis due to early death from sepsis after transplantation. The 44 included patients were divided into two cohorts according to the procurement technique: A warm dissection (n = 23; 52%) and a cold dissection group (n = 21; 48%). We compared early posttransplant graft function using the aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (T-bil), and prothrombin time (PT) values of the two groups from the first to seventh postoperative day.ResultThe AST values in the warm group were significantly greater than those in the cold group on postoperative days 3 and 5. In addition, the ALT values in the warm group were greater than those in the cold group on postoperative days 4, 5, and 6. Moreover, the T-bil values in the warm group were greater than those in the cold group on postoperative days 2, 3, 4, 5, 6, and 7. However, there were no differences in PT values.ConclusionDuring liver procurement for DDLT, rapid en bloc procurement with minimal manipulation after clamping the donor aorta achieved better early graft function posttransplantation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transplantation Proceedings - Volume 45, Issue 8, October 2013, Pages 2880-2885
نویسندگان
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