کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6250569 | 1611483 | 2016 | 9 صفحه PDF | دانلود رایگان |
BackgroundLocal excision of small (<10Â mm) rectal carcinoids is a standard treatment. Actual patterns of care and outcomes are understudied because of the rarity of this tumor.MethodsSurveillance, Epidemiology, and End Results database (1988 to 2012) was interrogated for rectal carcinoid patients. Chi-square testing and Kaplan-Meier survival analysis were used to compare survival outcomes.ResultsOf all, 11,329 patients were identified-9,605 with only localized disease. The majority (77%) underwent local excision only. Full rectal resection was performed more frequently for tumors greater than 10Â mm (11.7% to 12.2%) than for tumors less than 10Â mm (4.5% to 4.9%, P < .001), and for higher T stage (T1: 4.0%, T2: 11.4%, T3/4:30.4%, P < .001). Nonoperative management was more common after year 2000 (11.2% to 13.7%) than prior (7.4% to 8.5%, P < .001). Cancer-specific survival improved across time periods but did not differ between nonoperative, local excision, or surgical resection.ConclusionsNonexcisional management of small, localized rectal carcinoids is becoming more common and may offer equivalent survival to excision or resection.
Journal: The American Journal of Surgery - Volume 211, Issue 5, May 2016, Pages 877-885