کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6250680 1611488 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Southwestern Surgical CongressRegional recurrence in the era of sentinel lymph node biopsy
ترجمه فارسی عنوان
کنگره جراحی جنوب غربی مجددا تجربی در دوره بیوپسی گره لنفاوی نگهبان است
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی

BackgroundThe incidence of all-location regional recurrence after sentinel lymph node biopsy is not well documented. This study attempts to identify risk factors.MethodsA prospectively maintained database was queried to identify patients with a regional recurrence of breast cancer after a first operation for invasive unilateral breast cancer. Patients with regional recurrence were compared with those alive and disease free at 5 years.ResultsTwenty-one of 1,060 patients (2%) experienced a regional recurrence. Most patients (95%) underwent sentinel lymph node biopsy as their axillary staging. Those with regional recurrences had larger tumors (P < .001), higher stage disease (P < .001), more estrogen receptor- and triple-negative breast cancers (P < .001), and more positive lymph nodes (P = .007). Mastectomy (P = .001) and receipt of neoadjuvant and/or chemotherapy (P < .001) were more common among those with regional recurrences.ConclusionsRegional recurrence of breast cancer occurs infrequently. Risk factors include high-risk cancers, higher stage at presentation, nodal involvement, and need for therapies reflecting higher risk biology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 210, Issue 6, December 2015, Pages 1155-1161
نویسندگان
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