Transplantation/ImmunologySafety of living donor liver transplantation using older donors

BackgroundThere is limited information concerning older donors in living donor liver transplantation (LDLT). In the present study, we attempted to clarify whether it is safe to use older donors in LDLT.MethodsA total of 129 cases were reviewed in the present study. Donors and recipients were divided into group A (donors aged ≥50 y, n = 21) and group B (donors aged <50 y, n = 108). The pre-, intra-, and postoperative variables of the two groups were statistically compared.ResultsDonors' complication rates were 38.10% and 28.70% for groups A and B, respectively (P = 0.719). The overall 1-, 3-, and 5-y survival rates were 90%, 80%, and 66% for group A and 86%, 83%, and 75% for group B, respectively (P = 0.573). Similar Clavien III or more complication rates for recipients were observed.ConclusionsThe present study suggested that LDLT using older donors had no negative influence on the outcomes of both donors and recipients.