کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6265571 1614147 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research ReportMorphine-induced suppression of conditioned stimulus intake: Effects of stimulus type and insular cortex lesions
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Research ReportMorphine-induced suppression of conditioned stimulus intake: Effects of stimulus type and insular cortex lesions
چکیده انگلیسی

Intake of an unconditionally preferred taste stimulus (e.g., saccharin) is reduced by contingent administration of a drug of abuse (e.g., morphine). We examined the influence of insular cortex (IC) lesions on morphine-induced suppression of an olfactory cue and two taste stimuli with different levels of perceived innate reward value. Two major findings emerged from this study. First, morphine suppressed intake of an aqueous odor as well as each taste stimulus in neurologically intact rats. Second, IC lesions disrupted morphine-induced suppression of the taste stimuli but not the aqueous odor cue. These results indicate that the perceived innate reward value of the CS is not a factor that governs drug-induced intake suppression.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1292, 25 September 2009, Pages 52-60
نویسندگان
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