کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6271719 | 1614761 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Species differences in behavior and cell proliferation/survival in the adult brains of female meadow and prairie voles
ترجمه فارسی عنوان
تفاوت گونه ها در رفتار و تکثیر سلولی / زنده ماندن در مغز بزرگسالان زنبور عسل زنبور عسل و پرورش بلدرچین
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
intracerebroventricularDABPBSICVNGSPBT5-bromo-2′-deoxyuridine - 5-bromo-2'-deoxyuridineAmygdala - آمیگدال، بادامهAMY - امیoxytocin - اکسیتوسینBrdU - بروموداکسی اوریدینanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of variancedentate gyrus of the hippocampus - دندانه دار کردن قارچ از هیپوکامپnormal goat serum - سرم طبیعی بزphosphate buffer saline - فسفات بافر شورCSF - مایع مغزی نخاعیCerebrospinal fluid - مایع مغزی نخاعی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
Microtine rodents display diverse patterns of social organization and behaviors, and thus provide a useful model for studying the effects of the social environment on physiology and behavior. The current study compared the species differences and the effects of oxytocin (OT) on anxiety-like, social affiliation, and social recognition behaviors in female meadow voles (Microtus pennsylvanicus) and prairie voles (Microtus ochrogaster). Furthermore, cell proliferation and survival in the brains of adult female meadow and prairie voles were compared. We found that female meadow voles displayed a higher level of anxiety-like behavior but lower levels of social affiliation and social recognition compared to female prairie voles. In addition, meadow voles showed lower levels of cell proliferation (measured by Ki67 staining) and cell survival (measured by BrdU staining) in the ventromedial hypothalamus (VMH) and amygdala (AMY), but not the dentate gyrus of the hippocampus (DG), than prairie voles. Interestingly, the numbers of new cells in the VMH and AMY, but not DG, also correlated with anxiety-like, social affiliation, and social recognition behaviors in a brain region-specific manner. Finally, central OT treatment (200Â ng/kg, icv) did not lead to changes in behavior or cell proliferation/survival in the brain. Together, these data indicate a potential role of cell proliferation/survival in selected brain areas on different behaviors between vole species with distinct life strategies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 315, 19 February 2016, Pages 259-270
Journal: Neuroscience - Volume 315, 19 February 2016, Pages 259-270
نویسندگان
Y. Pan, Y. Liu, C. Lieberwirth, Z. Zhang, Z. Wang,