Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals

► CB1 receptors are present in both enkephalin and dynorphin terminals. ► Presynaptic and non-synaptic axonal membranes express CB1 receptors. ► CB1 receptors have distributions enabling retrograde and transaxonal signaling.