Invasion of lesion territory by regenerating fibers after spinal cord injury in adult macaque monkeys

► We examined the lesion territory in 18 macaque monkeys subjected to a cervical cord hemisection. ► Five monkeys received anti-Nogo-A antibody and BDNF, five only anti-Nogo-A and eight control antibody. ► The lesion territory was invaded with SMI-32-positive fibers, arising in majority from motoneurons. ► There was no difference in the number of SMI-32-positive fibers in the lesion territory in the three groups.