کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6275628 1614857 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The reduced glutathione and S-nitrosothiols levels in acute phase of experimental demyelination - Pathophysiological approach and possible clinical relevancy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
The reduced glutathione and S-nitrosothiols levels in acute phase of experimental demyelination - Pathophysiological approach and possible clinical relevancy
چکیده انگلیسی
► We explore GSH and S-nitrosothiols (RSNO) levels during acute phase of EAE. ► EAE animals were treated by aminoguanidine and N-acetyl-L-cysteine. ► The GSH levels are decreased and RSNO levels are increased during early phase of EAE. ► Increased GSH level and thiols content in CNS ameliorate clinical signs of EAE. ► GSH and RSNO appear to be the potential biomarkers and therapeutic targets in EAE.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 219, 6 September 2012, Pages 175-182
نویسندگان
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