کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6279105 | 1615068 | 2016 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of swimming exercise on morphine-induced reward and behavioral sensitization in maternally-separated rat pups in the conditioned place preference procedure
ترجمه فارسی عنوان
تأثیر تمرین شنا در پاداش ناشی از مورفین و حساسیت رفتاری در جنین های موش صحرایی جدا شده از مادران در روش ترجیح شرایط محیطی
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کلمات کلیدی
جدایی مادران، ورزش شنا، ترجیح محل مواجه، مورفین، حساسیت رفتاری،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
This study was designed to examine the effects of swimming exercise during adolescence on morphine-induced conditioned place preference (CPP) and behavioral sensitization in maternally separated male and female rat pups. Male Wistar rats were allowed to mate with female virgin Wistar rats. Pups were separated from the dam daily for 180Â min during postnatal days 2-14. All pups were weaned on day 21.The exercising pups were allowed to swim (60Â min/d, five days per a week, for 30Â days) during adolescence. Then, rat pups were tested for behavioral sensitization and the CPP induced by morphine. Maternal separation produced a significant increase in morphine-induced CPP in both sexes, behavioral sensitization in male pups and tolerance to morphine-induced motor activity in female pups. Swimmer pups separated from the dam exhibited a decrease in morphine-induced CPP in both sexes and behavioral sensitization in male pups than those of their control pups. The present results have shown that swimming exercise during adolescence may exert a protective effect against morphine-induced reward and behavioral sensitization in adult male and female rats following maternal separation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 631, 19 September 2016, Pages 79-84
Journal: Neuroscience Letters - Volume 631, 19 September 2016, Pages 79-84
نویسندگان
Atiyeh Taghavi-Khalil Abad, Hossein (Associate Professor), Imanollah Bigdeli,