Polymorphisms in immune/inflammatory cytokine genes are related to Parkinson's disease with cognitive impairment in the Han Chinese population

► We examined IL-10/IL-17A/IFN-γ polymorphisms in PD and PD-cognitive impairment. ► There were no significant links between IL-10/IL-17A/IFN-γ polymorphism and PD. ► IL-17A rs8193036/IL-10 1082G/A may be associated with cognitive impairment in PD. ► Polymorphisms of cytokine genes may be involved in the cognitive impairment of PD.