Flavan-3-ol compounds prevent pentylenetetrazol-induced oxidative damage in rats without producing mutations and genotoxicity

► We investigated the protective effects of administering flavan-3-ol extract in rats. ► The extract shows protective effects against neuronal and hepatic damage. ► The extract was shown to be non-genotoxic and non-mutagenic. ► This extract may be used to develop new therapeutic agent against seizures disorder.