Transcranial direct current stimulation (tDCS) priming of 1Â Hz repetitive transcranial magnetic stimulation (rTMS) modulates experimental pain thresholds

► Priming motor cortex with tDCS before 1 Hz rTMS standardizes its effects. ► This technique is applied to experimental pain thresholds. ► Cathodal tDCS - 1 Hz rTMS increased heat and cold pain thresholds. ► Anodal tDCS - 1 Hz rTMS decreased cold pain thresholds. ► tDCS priming may have applications in pain relief in the clinic.