Mental rotation of a letter, hand and complex scene in microgravity

► The study compared three typical mental rotation tasks in weightlessness and 1 G. ► We provided visual and tactile vertical cues to provide a more realistic surrounding. ► Reaction time and error rate of all stimuli showed typical behavior. ► Reaction time and error rate were equal in microgravity and 1 G. ► Allocentric and egocentric mental rotation were both not impaired in microgravity.