Differential calcium dependence in basal and forskolin-potentiated spontaneous transmitter release in basolateral amygdala neurons

► Both basal and potentiated spontaneous release are regulated by extracellular Ca2+. ► Basal, but not potentiated, spontaneous release is regulated by intracellular Ca2+. ► CaSR inhibitor has no effect on basal spontaneous release. ► CaSR inhibitor increases the potentiated spontaneous release.