Eye enucleation activates the transcription nuclear factor kappa-B in the rat superior colliculus

► Ocular enucleation leads to NF-κB activation in the superior colliculus. ► NF-κB subunits p65 and p50 protein levels increased after visual system deafferentation. ► Dexamethasone was able to attenuate NF-κB activation in the superior colliculus.