The concentrations of serum, plasma and platelet BDNF are all increased by treadmill VO2max performance in healthy college men

► One-bout aerobic exercise induces increased BDNF levels in serum and plasma and within platelets. ► Basal BDNF levels are inversely correlated with cardiorespiratory fitness levels. ► BDNF immediately after exercise is positively correlated with cardiorespiratory fitness. ► Cardiorespiratory fitness levels are not correlated with platelet counts.