Electroconvulsive stimulations prevent chronic stress-induced increases in L-type calcium channel mRNAs in the hippocampus and basolateral amygdala

► Stress upregulates Cav1.2 and Cav1.3 channels in a brain region specific manner. ► ECS has the opposite effect. ► ECS effects on Cav1.2 channel expression are generally specific to stressed animals. ► ECS effects on Cav1.3 channel expression appear to be independent of stress status. ► This is consistent with intracellular calcium ion dysfunction in affective disorders.