Influence of COX-2 and OXTR polymorphisms on treatment outcome in treatment resistant depression

► The aim of the present paper is to highlight the genetics of treatment resistant depression (TRD). ► COX-2 and OXTR are interesting candidate genes for association with TRD. ► 372 patients, recruited in the context of a TRD study, were genotyped for COX-2 and OXTR SNPs. ► We found no association between these SNPs and treatment resistance, response or remission.