Cerebral endothelial derived vascular endothelial growth factor promotes the migration but not the proliferation of oligodendrocyte precursor cells in vitro

► Conditioned media from cerebral endothelial cells promoted both OPC (oligodendrocyte precursor cell) migration and proliferation. ► Endothelial-derived VEGF-A played a central role in the OPC migration. ► Endothelial-VEGF-A did not participate in the OPC proliferation.